Principal Stratification -- a Goal or a Tool?
نویسندگان
چکیده
منابع مشابه
Principal stratification--a goal or a tool?
Principal stratification has recently become a popular tool to address certain causal inference questions, particularly in dealing with post-randomization factors in randomized trials. Here, we analyze the conceptual basis for this framework and invite response to clarify the value of principal stratification in estimating causal effects of interest.
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This commentary takes up Pearl's welcome challenge to clearly articulate the scientific value of principal stratification estimands that we and colleagues have investigated, in the area of randomized placebo-controlled preventive vaccine efficacy trials, especially trials of HIV vaccines. After briefly arguing that certain principal stratification estimands for studying vaccine effects on post-...
متن کاملPrincipal stratification: a broader vision.
*Corresponding author: Ian Shrier, Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E2, Canada, E-mail: [email protected] Jay S. Kaufman: E-mail: [email protected], Robert W. Platt: E-mail: [email protected], Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University...
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15 صفحه اولA refreshing account of principal stratification.
Pearl (2011) invites researchers to contribute to a discussion on the logic and utility of principal stratification in causal inference, raising some thought-provoking questions. In our commentary, we discuss the role of principal stratification in causal inference, describing why we view the principal stratification framework as useful for addressing causal inference problems where causal esti...
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ژورنال
عنوان ژورنال: The International Journal of Biostatistics
سال: 2011
ISSN: 1557-4679
DOI: 10.2202/1557-4679.1322